ASSOC.PROF. P.HD. HO DINH TRUNG DEFENDER 1

2. Assoc.Prof. P.hD. Ho Dinh Trung Defender 1:... Instituion:... Defender 2:... Institution:... The thesis will be defended in front of the Institutional Defense Committee at. the National Institute of Malariology, Parasitology, and Entomology at………2020 The thesis can be found at: - The National library; - The library of the National Institute of Malariology, Parasitology and Entomology INTRODUCTION Dengue hemorrhagic fever (DHF) is a communicable disease of group B caused by the virus of the Flaviviridae family, transmitted by the female mosquito Aedes [1]. Among the 5 Southeast Asian countries with the highest dengue burden [5], Vietnam has implemented epidemiological surveillance measures for dengue and proactively prevented dengue transmitting mosquitoes to cut off the source of dengue virus transmission. Mosquitoes suck the blood of sick people and pass them to healthy people when they bite blood. Two popular measures to prevent dengue transmission mosquitoes that are recommended by WHO in the world and the Ministry of Health of Vietnam instructed in the national Dengue control program are the use of ULV spray to against adult mosquitoes and larvicide [6], [7]. Among the provinces with high prevalence of dengue, Khanh Hoa in the Central region has the highest number of dengue per 100,000 population in many years [13]. To answer the question about the current status of the vector of dengue transmission in some districts with high risk of dengue fever such as Dien Khanh district, Khanh Hoa province, there are changes in some biological characteristics such as species composition, behavior, price can stay, reproductive nests; Does sensitivity to insecticides reduce the effectiveness of currently commonly used insecticides when spraying, killing larvae, mosquitoes transmitting dengue? At the same time, the study also evaluated some new insecticides for the method of spraying ULV and killing mosquito larvae Ae.aegypti recommended by WHO for the first time field trial in Vietnam, which is the basis for proposing measures and The insecticide is suitable for areas with high prevalence of SXHD and a high risk of mosquitoes Ae.aegypti has been resistant to the Pyrethroid group insecticide. Therefore, we conduct the project "Study on the status of Dengue vectors and effectiveness of Aedes mosquito control measures in Dien Khanh district, Khanh Hoa province, the period 2015 - 2019" as follows: