26·106 (9.15·104)THEH222⁄H208 RATIOS PROVIDE INFORMATION ON THE LIKE...
1.26·10
6
(9.15·104
)Theh222⁄h208 ratios provide information on the likelihood of thealpha-helix being in isolation or being found within a coiled coilstructure [30,31,33]. A ratio > 1.0 typically indicates the latter,whereas a ratio of0.9 or less indicates the presence of a helix inisolation. For all dimeric pairs, except the wild-type structure (whichis known to interact with low affinity), the ratio is > 0.9, supporting